Biological Services

Chaim Kahana, Head


Biological Computing Unit (Dr. L. Esterman, in charge)

Databases for molecular biology and molecular modeling-management, installation and updating.

Microcomputers and workstations-applications in biological sciences.

Equipment: Digital Alpha 8200 server, several workstations, some of which are smart X-terminals.

Bioinformatics Unit (Dr. J. Prilusky, in charge)

Bioinformatics databases: Retrieval, optimization and programming.

Equipment: A Sun Enterprise 10000 server, 4 Sun SPARCstations(tm), Inherit 670(tm) Sequence Analysis System with 2 Fast Data Finder(tm) boards, 2 Digital Alpha stations.

DNA Analysis Unit (T. Mehman, in charge)

Automatic DNA sequence analysis; genotyping.

Equipment: Five automatic DNA sequencers (2 ABI model 377 and 3 ABI model 373), 672 Genescan(tm) Software. Auxiliary equipment including 4 thermal cyclers and 2 GeneQuant microspectrophotometers.

Protein analysis Unit (N. Tal and Dr. A. Rabinkov, in charge)

Preparation and HPLC separation of proteolytic digests, automatic protein and peptide microsequencing in solution and as electroblotted bands, measurement of protein-protein interactions and similar interactions.

Equipment: Protein microsequencer (Model 491, Procise), HPLC, BIAcore 2000, densitometer.

Flow Cytometry Unit (Dr. A. Sharp and E. Ariel, in charge)

Analysis and sterile sorting of cells and sub-cellular organelles. Sorting parameters are: cell number and size, granularity and shape, DNA, RNA and protein contents, surface and intracellular antigens, intracellular calcium or pH, membrane fluidity and permeability, enzyme activity, endocytosis.

Equipment: Two fluorescence-activated cell sorters (FACSTAR plus and FACSVantage), FACSCAN and FACSORT analyzer and a fluorescent microscope.

Bacteriology Unit (I. Segal, in charge)

Medium scale fermentation of microorganisms; downstream processing of fermentation products; preparation of agar plates; preparation of growth media for bacterial, algal, fungal and cell culturing; sterilization of media and equipment.

Equipment: Two 10-liter fermentors, autoclaves, continuous centrifuges, ultrasonic sonicator and other auxiliary equipment for bacterial and cell culture work.

Irradiation Unit (G. Ben-Moshe, in charge)

X-ray irradiation; Gamma ray irradiation; consultation and shielding design.

Equipment: One heavy duty and one low energy X-ray machines, two gamma ray sources.

Electronic Service Unit (A. Auerbach, in charge)

Design and assembly of new electronic equipment, modification of existing equipment, repair, upgrade and maintenance of Macintosh computers and peripheral equipment, repair and maintenance of electronic equipment.

Monoclonal and Polyclonal Antibody Unit (Dr. O. Leytner, in charge)

Development of hybridoma cells, preparation of monoclonal antibodies from existing hybridoma cells, preparation of polyclonal antibodies.

Peptide & Oligonucleotide Synthesis Unit (Dr. O. Goldberg, in charge)

Synthesis of oligonucleotides and peptides.

Equipment: Three oligonucleotide synthesizers (Expedite 8900 Nucleic Acid Synthesis System), one peptide synthesizer (ABI Model 432).

 


 This file was last modified on 08/15/2004 15:13:49

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